In 1912 Sonora, Mexico, Arizona lawman Lyedecker chases Yaqui Joe, a half-Yaqui, half-white bank robber who has stolen $6,000. Both men are captured by the Mexican general Verdugo.
Lyedecker learns that Joe used the loot to buy 100 rifles for the Yaqui people, who are being repressed by the government. Lyedecker is not interested in Joe’s motive, and intends to recover the money and apprehend Joe to further his career.
The two men escape a Mexican firing squad and flee to the hills, where they are joined by Sarita, a beautiful Indian revolutionary. Sarita has a vendetta against the soldiers, who murdered her father. The fugitives become allies.
Leading the Yaqui against Verdugo’s forces, they ambush and derail the General’s train and overcome his soldiers in an extended firefight.