The film opens with Reed (Christopher Abbott), standing over his infant daughter with an ice pick. His wife sleeps across the room unaware. He is not going to kill the baby, but is practicing for a future murder. He has convinced them that he is going on a business trip, but actually intends to rent a hotel room, hire the services of a sex worker, and kill her, thereby redirecting his murderous impulses away from his child.
However, when the appointed time arrives, Jackie (Mia Wasikowska) has arrived instead of his intended victim. She brings with her a collection of kinky fetish gear and a sadistic impulse. After a bad first encounter, she hides in the bathroom, before the evening really begins to become crazy as the two engage in a twisted game of cat and mouse.