Following their successful heist in Brazil, Dominic “Dom” Toretto and his professional criminal crew have fled around the world and are living peacefully: Dom lives with Elena Neves; his sister Mia lives with Brian O’Conner and their son, Jack; Gisele Yashar and Han Seoul-Oh are together; and Roman Pearce and Tej Parker live in luxury. Meanwhile, DSS agents Luke Hobbs and Riley Hicks investigate the destruction of a Russian military convoy by a crew led by former British SAS Major and special ops soldier Owen Shaw. Hobbs persuades Dom to help capture Shaw by showing him a photo of his supposedly murdered girlfriend, Letty Ortiz. Dom and his crew accept the mission in exchange for their amnesty and allowing them to return to the United States.
In London, Shaw’s hideout is found, but this is revealed to be a trap, distracting them and the police while Shaw’s crew performs a heist at an Interpol building. Shaw flees by car, detonating his hideout and disabling most of the police, leaving Dom, Brian, Tej, Roman, Han, Gisele, Hobbs, and Riley to pursue him. Letty arrives to help Shaw, shooting Dom without hesitation before escaping. Back at their headquarters, Hobbs tells Dom’s crew that Shaw is stealing components to create a deadly device, intending to sell it to the highest bidder. Meanwhile, Shaw’s investigation into the opposing crew reveals Letty’s relationship with Dom, but she is revealed to be suffering from amnesia. Dominic’s crew learns that Shaw is connected to a drug lord who was imprisoned by Brian, Arturo Braga. Brian returns to Los Angeles as a prisoner to question Braga, who says Letty survived the explosion that seemingly killed her; Shaw took her in after discovering her amnesia. With FBI’s help, Brian is released from prison, regrouping with the team in London.
Dom challenges Letty in a street racing competition; afterward, he returns her cross necklace he had kept. After Letty leaves, Shaw offers Dom a chance to walk away, threatening to otherwise hurt his family, but Dom refuses. Tej tracks Shaw’s next attack to a Spanish NATO base. Shaw’s crew assaults a highway military convoy carrying a computer chip to complete his device. Dom’s crew interferes, while Shaw, accompanied by Letty, commandeers a tank, destroying cars en route. Brian and Roman manage to flip the tank before it causes further damage, resulting in Letty being thrown from the vehicle, though Dom saves her. Shaw and his crew are captured, but reveal Mia has been kidnapped by Shaw’s henchmen Vegh and Klaus. Hobbs is forced to release Shaw, and Riley, revealed to be Shaw’s covert accomplice, leaves with him; Letty chooses to remain with Dom.
Shaw’s group board a moving Antonov An-124 on a runway as Dom’s crew gives chase. Dom, Letty, and Brian board the craft; Brian rescues Mia, escaping in an onboard car. The plane attempts to take-off but is held down by excess weight as the rest of the team tether the plane to their vehicles. Gisele sacrifices herself to save Han from Shaw’s henchman. Letty kills Riley and escapes with Hobbs to safety, but Dom pursues Shaw and the computer chip. As the plane crashes into the ground, Shaw is thrown from it, and Dom drives a car out of the exploding plane. Dom reunites with his crew and gives the chip to Hobbs to secure their pardons. Dom and the others return to his old family home in Los Angeles. Hobbs and Elena, now working together, arrive to confirm the crew’s freedom; Elena accepts that Dom loves Letty. As Roman says grace over the crew’s meal, Dom asks Letty if the gathering feels familiar; she answers “No, but it feels like home.”
In a mid-credits scene, Han is involved in a car chase when he is suddenly broadsided by an oncoming car. The driver walks away from the scene after leaving Letty’s cross necklace by the crash, and calls Dom as Han’s car explodes, supposedly killing Han. The driver then says to Dom: “Dominic Toretto. You don’t know me. You’re about to.”