In the city of New Orleans, hitman Jimmy Bobo and his partner Louis Blanchard kill a corrupt former MPDC policeman, Hank Greely, although Bobo leaves a prostitute, Lola, alive. Later, at a bar, Blanchard is murdered by another hitman, Keegan, who also attempts to kill Bobo but fails.
Washington, D.C., Detective Taylor Kwon arrives in New Orleans to investigate his former partner’s death and meets Lieutenant Lebreton, who informs him Lola confirmed Greely was assassinated. Kwon goes to the morgue, and, after seeing Blanchard’s body and finding out who he is, he deduces that Blanchard and Bobo killed Greely. Meanwhile, Keegan meets with his employer, Robert Morel, and Morel’s lawyer Marcus Baptiste. Baptiste reveals that Greely tried to blackmail Morel, and provided local mobster Baby Jack with a file detailing Morel’s illegal operations. Keegan later kills Baby Jack and his men and retrieves the file.
Kwon meets Bobo in a bar and informs him that he knows Bobo and Blanchard killed Greely. Bobo leaves, and when Kwon tries to follow him, he is attacked by corrupt cops who were ordered by Morel to prevent Kwon from further investigating about Greely. Kwon manages to disarm and gun down one of the corrupt cops but is wounded by the other. Bobo rescues Kwon by running over the other cop and takes him to a tattoo parlor, where Bobo’s estranged daughter, Lisa, treats Kwon’s wounds. They later go to a massage parlor where Bobo interrogates Ronnie Earl, the middleman who hired Bobo and Blanchard on Morel’s behalf. Ronnie Earl tries to kill Bobo, but Bobo manages to kill him, although his gun jams. Bobo later confronts Kwon, who admits to having tampered with Bobo’s gun, nearly causing his death. Bobo and Kwon agree to work together.
Bobo and Kwon kidnap Baptiste and take him to Bobo’s house, where he is forced to give them a flash drive detailing Morel’s plans to acquire housing projects and demolish them to build office buildings and reveals Keegan is an ex-mercenary hired to be Morel’s enforcer. Afterwards, Bobo shoots him in the head. Keegan and his men trace Baptiste’s cellphone to Bobo’s house, but Bobo and Kwon are able to escape and detonate a bomb, killing Keegan’s men. Keegan escapes and swears revenge on Bobo. Angered at Bobo’s methods, Kwon abandons him and continues alone.
Kwon meets with Lieutenant Lebreton to ask for his help, but Lebreton tries to kill him, as he is also on Morel’s payroll. Bobo kills him and saves Kwon. Meanwhile, Keegan learns about Lisa and kidnaps her. Morel then calls Bobo and offers to trade Lisa for the flash drive. Bobo agrees, and meets with Morel in an abandoned warehouse, where he delivers the flash drive to him and Lisa is returned to him, while Kwon infiltrates the building to arrest Morel killing several of Morels men along way. Keegan becomes furious when Bobo is allowed to leave; he kills Morel and his men before confronting Bobo; they fight until Bobo stabs Keegan in the throat and Kwon shoots him dead from afar.
Kwon retrieves the flash drive and Bobo shoots him in the shoulder to make it appear as if Kwon failed to capture him. Lisa decides to stay with Kwon waiting for the police and Bobo leaves. He later meets Kwon at a bar, where Kwon tells him he did not mention Bobo’s involvement to the police this time, but if Bobo continues in the business, Kwon will take him down. Bobo welcomes him to try and drives off into the night.